Source::AP
London,
British scientists are starting a study Thursday to find out if it’s OK to mix and match COVID-19 vaccines. The vaccines being rolled out now require two doses, and people are supposed to get two shots of the same kind, weeks apart.
Guidelines in Britain and the U.S. say the vaccines aren’t interchangeable, but can be mixed if the same kind isn’t available for the second dose or if it’s not known what was given for the first shot. Participants in the government-funded study will get one shot of the AstraZeneca vaccine followed by a dose from Pfizer, or vice versa.
COVID-19 vaccines all train the body to recognize the coronavirus, mostly the spike protein that coats it. The ones from AstraZeneca and Pfizer use different technologies. AstraZeneca’s uses a common cold virus to carry the spike gene into the body. Pfizer’s is made by putting a piece of genetic code called mRNA — the instructions for that spike protein — inside a little ball of fat.
If the vaccines can be used interchangeably, “this will greatly increase the flexibility of vaccine delivery,” he said in a statement. ”(It) could provide clues as to how to increase the breadth of protection against new virus strains.”
In recent weeks, Britain, the European Union and numerous other countries have been hit with vaccine supply issues: AstraZeneca said it would dramatically reduce the expected number of doses it could deliver due to manufacturing delays and Pfizer also slowed deliveries while it upgraded its Belgian factory.
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